HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Aminomethyl-4-(1,1-dimethylethyl)-6-methylsulfamoylphenol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Acetamidomethyl-4-(1,1-dimethylethyl)-6-methylsulfamoylphenol | HCID 13210350 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Aminomethyl-4-(1,1-dimethylethyl)-6-methylsulfamoylphenol hydrochloride | HCID 21296908 | — |
Reaction Steps
4.9 g (0.016 mole) of 6-acetamidomethyl-4-(1,1-dimethylethyl)-2-methylsulfamoylphenol in a mixture of 30 ml of ethanol and 10 ml of concentrated hydrochloric acid are heated under reflux for 8 hours. Evaporation and recrystallization from methanol/ether gives white crystals of melting point 238°-240° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04766241 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-da580e455ab5437193e566ed18538d68 |
| Source note | uspto-grants-1988_08 |