HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Aminoethyl)piperidine → [6-Methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophen-3-yl]-[6-(2-piperidin-1-yl-ethylamino)-pyridin-3-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Aminoethyl)piperidine | HCID 33944 | — |
| Reactant | (6-Chloro-pyridin-3-yl)-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophen-3-yl]-methanone | HCID 23512898 | — |
| Product | [6-Methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophen-3-yl]-[6-(2-piperidin-1-yl-ethylamino)-pyridin-3-yl]-methanone | HCID 23512913 | — |
Reaction Steps
The coupling of the product from Step 1, Example 5 (6-Chloro-pyridin-3-yl)-[6-methoxy-2-(4-methoxy-phenyl) -benzo[b]thiophen-3-yl]-methanone) and 1-(2-Aminoethyl)-piperidine was carried out as in Example 5, Step 2 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06756388B1 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-be74a8820bc049ca8c2666ddf009a282 |
| Source note | uspto-grants-2004_06 |