HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-2-cyclohexylbenzo[b]thiophene → Methanone, (2-cyclohexyl-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-2-cyclohexylbenzo[b]thiophene | HCID 10879420 | — |
| Reactant | 4-(2-(Piperidin-1-yl)ethoxy)benzoyl chloride | HCID 11119066 | — |
| Product | Methanone, (2-cyclohexyl-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)- | HCID 9825662 | — |
Reaction Steps
The product from Example 19, Step 2 and 4-(2-Piperidin-1-yl-ethoxy)-benzoyl chloride were coupled according to procedure C above and the methyl protecting group removed using etanethiol/aluminum trichloride to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06756388B1 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-3dc8d845d7c64643bd07edb32d08d73c |
| Source note | uspto-grants-2004_06 |