HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxide → 4-oxo-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxide | HCID 961 | — |
| Reactant | Ethyl 4-oxochromane-2-carboxylate | HCID 12909077 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-oxo-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid | HCID 9855708 | — |
Reaction Steps
The carboxylic acid group of the compound of Example 2 (ethyl 4-oxochromane-2-carboxylate) was treated with a metallic hydroxide base in ethanol, and then the aqueous layer was treated with an acid to form the free acid, which was washed with water and then dried to yield 3 g of 4-oxo-chromane-2-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06756403B2 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-5196757bd2644a829bbc28bfa7a7188e |
| Source note | uspto-grants-2004_06 |