HCID 12993799, compound → HCID 12993800, compound

Participants

Reaction Steps

0.30 g of ethyl 5-chloro-2-methyl-3-(3-methylisoxazol-5-yl)-4-methylsulfonylbenzoate was dissolved in 20 ml of ethanol. After the reaction system was purged by nitrogen, 0.02 g of 5% palladium-carbon was added. The system was purged by hydrogen. A rubber ball filled with hydrogen was attached and the solution was stirred at room temperature for 3 hours. The palladium-carbon was removed from the reaction solution by filtration. The solvent was distilled off under reduced pressure to give 0.28 g of the title compound as white crystals. Melting point: 83-86° C.

Provenance & Evidence