HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19841578, compound → Pyrimidine, 2-(1,1-dimethylethyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19841578 | HCID 19841578 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Pyrimidine, 2-(1,1-dimethylethyl)- | HCID 94597 | — |
Reaction Steps
A pyridine solution of 3-aminopropylpivalamide (approximately 35 percent by weight aminoamide) was fed continuously to a heated 1"×20" reactor maintained at 330° to 345° C. The reactor was packed with 50 g of 0.5 percent palladium on alumina. After removal of pyridine by distillation, the product, 2-t-butylpyrimidine was obtained, b.p. 160° to 163° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04376201 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-7bca7ea3759d49cebee4d02b2af5cc2d |
| Source note | uspto-grants-1983_03 |