Water → Ethyl (2Z)-2-methoxyimino-3-oxo-butanoate

HRID 354649Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 354649
[C:1](=O)([O-])[O-].[K+].[K+].[C:7]([C:10](=[N:16][OH:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12])(=[O:9])[CH3:8].S(OC)(OC)(=O)=O.O>CC(C)=O>[C:7]([C:10](=[N:16][O:17][CH3:1])[C:11]([O:13][CH2:14][CH3:15])=[O:12])(=[O:9])[CH3:8]

Komponenten

6

Edukt 4

HCID 962WaterHCID 6497Dimethyl SulfateHCID 11430Potassium CarbonateHCID 178472877HCID 178472877, Verbindung

Produkt 1

HCID 43493Ethyl (2Z)-2-methoxyimino-3-oxo-butanoateAusbeute 94,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

234 g of potassium carbonate were added at 10° C. under a nitrogen atmosphere to a mixture of 180 g of raw ethyl 2-acetyl-2-hydroxyiminoacetate in 900 ml of pure acetone and then 103 ml of dimethyl sulfate were added thereto. The mixture was stirred at room temperature for 3 hours and was then poured into ice and 4 liters of water were added. The mixture was extracted with methylene chloride and the extracts were washed with water, dried and distilled to dryness to obtain 185 g of ethyl 2-acetyl-2-methoxyiminoacetate.

Aufarbeitung

  1. additionwere added
  2. extractionThe mixture was extracted with methylene chloride
  3. washthe extracts were washed with water
  4. customdried
  5. distillationdistilled to dryness

Quellen und Nachweise

ORD-Eintrag
ord-08816710fd1140bcb319dc3a163622d2
Quelldatensatz
uspto-grants-1983_03
Patentnummer
US04376203

Notizen zur Reaktion

Wird geladen…