5-(o-fluorophenyl)-1,3-dihydro-1,3,3-trimethyl-7-nitro-2H-1,4-benzodiazepin-2-one → 2-Amino-5-nitro-2'-chlorobenzophenone

HRID 354743Notes

Reaction equation

HRID 354743 reaction equation
FC1C=CC=CC=1C1C2C=C([N+]([O-])=O)C=CC=2N(C)C(=O)C(C)(C)N=1.NC(C)(C)C([NH:30][C:31]1[CH:36]=[CH:35][C:34]([N+:37]([O-:39])=[O:38])=[CH:33][C:32]=1[C:40](=[O:48])[C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][C:42]=1[Cl:47])=O>>[NH2:30][C:31]1[CH:36]=[CH:35][C:34]([N+:37]([O-:39])=[O:38])=[CH:33][C:32]=1[C:40]([C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][C:42]=1[Cl:47])=[O:48]

Participants

3

Reactant 2

HCID 205061565-(o-fluorophenyl)-1,3-dihydro-1,3,3-trimethyl-7-nitro-2H-1,4-benzodiazepin-2-oneHCID 205061692-Amino-2'-(o-chlorobenzoyl)-2-methyl-4'-nitro-propionanilide

Product 1

HCID 748302-Amino-5-nitro-2'-chlorobenzophenone

Procedure

From 70 g (0.25 mol) of 2-amino-5-nitro-2'-chlorobenzophenone there is obtained, in analogy to the details in paragraph (a) of Example 1, 2-amino-2'-(o-chlorobenzoyl)-2-methyl-4'-nitro-propionanilide of melting point 138°-139° (ether/petroleum ether).

Sources & evidence

ORD record
ord-28c573fa77904a8f9841e0698735e739
Source dataset
uspto-grants-1983_03
Patent number
US04377522

Reaction notes

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