HCID 20506172, compound → HCID 20506160, compound

Participants

Reaction Steps

From 6.5 g (0.018 mol) of 7-amino-5-(o-chlorophenyl)-1,3-dihydro-1-(2-hydroxyethyl)-3,3-dimethyl-2H-1,4-benzodiazepin-2-one there is obtained, in analogy to the details in paragraph (b) of Example 4, via [5-(o-chlorophenyl)-2,3-dihydro-1-(2-hydroxyethyl)-3,3-dimethyl-2-oxo-1H-1,4-benzodiazepin-7-yl]isocyanate, 1,-[5-o-chlorophenyl)-2,3-dihydro-1-(2-hydroxyethyl)-3,3-dimethyl-2-oxo-1H-1,4-benzodiazepin-7-yl]-3-(2-hydroxyethyl)urea of melting point 175°-176° (ethanol/ethyl acetate).

Provenance & Evidence