Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 354807Generated: October 30, 2026

Ammonia → 2,6-Dichloro-7-methoxyquinazolin-4-amine

https://huagongshe.com/reaction/354807

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant2,4,6-Trichloro-7-methoxyquinazolineHCID 12920005—
Product2,6-Dichloro-7-methoxyquinazolin-4-amineHCID 1292000758%

Reaction Steps

Reaction of 2,4,6-trichloro-7-methoxyquinazoline with ammonia as described above afforded 2,6-dichloro-4-amino-7-methoxyquinazoline as a white solid, M.P., 300° C. in 58% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04377581
Source datasetuspto-grants-1983_03
ORD IDord-e786d94270b54d9cbdcca4a573edef13
Source noteuspto-grants-1983_03