HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxypyrrolidine → HCID 20506397, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxypyrrolidine | HCID 98210 | — |
| Reactant | HCID 12920006 | HCID 12920006 | — |
| Solvent | Isoamyl Alcohol | HCID 31260 | — |
| Product | HCID 20506397 | HCID 20506397 | — |
Reaction Steps
A mixture of 4-amino-2,6-dichloro-7,8-dimethoxyquinazoline (5.48 g., 0.020 mole) and 3-pyrrolidinol (2.18 g., 0.025 mole) in 150 ml. of isoamyl alcohol is heated at reflux for five hours then cooled in ice. The precipitated product is collected by filtration and purified by recrystallization to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04377581 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-9cf45c9b3e0b4be6a0f8e3a39a7ffcec |
| Source note | uspto-grants-1983_03 |