Hydrochloric Acid → HCID 20506542, compound

HRID 354909Notes

Reaction equation

HRID 354909 reaction equation
[C:1]1([CH:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:8]2([OH:16])[CH2:12][S:11][C:10](=[N:13][CH3:14])[N:9]2[CH3:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:23]>C(O)C>[ClH:23].[C:17]1([CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[C:8]2([OH:16])[CH2:12][S:11][C:10](=[N:13][CH3:14])[N:9]2[CH3:15])[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13101029HCID 13101029, compound

Product 1

HCID 20506542HCID 20506542, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

To a warm solution of 4.80 g. of 3-methyl-2-methylimino-4-diphenylmethyl-4-thiazolidinol (Example 11) in 50 ml. of ethanol is added 15 ml. of 3.48 N ethanolic hydrochloric acid. The solution is diluted to 200 ml. with ethanol and allowed to stand. The crystals are recovered by filtration, washed with ethanol and dried, giving 4.59 g. of the desired product, m.p. 252°-254° C. (dec.).

Workup

  1. additionThe solution is diluted to 200 ml
  2. filtrationThe crystals are recovered by filtration
  3. washwashed with ethanol
  4. customdried
  5. customgiving 4.59 g

Sources & evidence

ORD record
ord-6db295d2079342d9883fe123525d09ba
Source dataset
uspto-grants-1983_03
Patent number
US04377589

Reaction notes

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