反应详情

1-Acetyl-3-benzyloxypiperidine (0.043 mole), sodium hydroxide (0.086 mole) and water (30 ml.) are combined and refluxed for 24 hours. The reaction mixture is saturated with potassium carbonate and extracted three times with ether. The ether is removed by evaporation and the yellow oil is distilled at 92°-94° C. (0.3 mm Hg.).

1. temperaturerefluxed for 24 hours
2. extractionextracted three times with ether
3. customThe ether is removed by evaporation
4. distillationthe yellow oil is distilled at 92°-94° C. (0.3 mm Hg.)