Hydrochloric Acid → HCID 54071267, compound

Participants

Reaction Conditions

Reaction Steps

In a two-necked round-bottomed flask, 98 mg (0.52 mM) of methyl (S)-3-fluorononanoate and 1 ml of acetic acid were placed. To the mixture, 1 ml of concentrated hydrochloric acid was added, followed by stirring for 4 hours at 90° C. After the reaction, ice water was added to the reaction mixture, followed by extraction with Et2O. The organic layer was sufficiently washed with distilled water and dried with anhydrous magnesium sulfate, followed by distilling-off of the solvent under reduced pressure to obtain 78 mg (0.44 mM) of (S)-3-fluorononanoic acid.

Provenance & Evidence