反应详情

A 1.0M solution of Compound 24 in CH2Cl2 is added to a suspension of pyridinium chlorochromate (4.0 eq) in CH2Cl2 at 20° C. with stirring. The reaction is stirred for 24 hours and filtered through a pad of diatomaceous earth. The filtrate is concentrated in vacuo and then purified by silica gel column chromatography (eluted with Hex/EtOAc) to yield Compound 25.

1. stirringThe reaction is stirred for 24 hours
2. filtrationfiltered through a pad of diatomaceous earth
3. concentrationThe filtrate is concentrated in vacuo
4. custompurified by silica gel column chromatography (eluted with Hex/EtOAc)