HRID355501

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(=O)OC[C@H]1O[C@@H](n2cnc(C(=O)O)c2N)[C@H](OC(C)=O)[C@@H]1OC(C)=O

HCID11811108

未命名化合物

结构：OC[C@H]1O[C@@H](n2cnc3c2N=CNC[C@H]3O)[C@H](O)[C@@H]1O

HCID178521061

未命名化合物

PRODUCTS

生成物

结构：O=C1CNC=Nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

HCID178516781

未命名化合物

PROCEDURE

实验过程

Another method also known for the synthesis of coformycin comprises preparing and using 5-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole-4-carboxylic acid as a starting material which is processed by multi-stage reactions to produce 3-(β-D-ribofuranosyl)-6,7-dihydroimidazo[4,5-d][1,3]diazepin-8(3H)-one as an intermediate, followed by reducing the intermediate (see H. J. Thomas et al., "Nucleosides & Nucleotides", 5, No. 4, pp. 431-439, 1986).

WORKUP

后处理

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