反应详情

温度

60 °C

245 mg of the compound prepared in (3) above was dissolved into 40 ml of 3N hydrochloric acid and heated at 60° C. for 1 hour while stirring. After cooling to 0° C., the reaction solution was neutralized with sodium carbonate and extracted with chloroform. The extract was dried over magnesium sulfate. The residue obtained after the removal of the solvent was recrystallized in ethyl acetate and hexane to obtain 150 mg of the title compound.

1. temperatureAfter cooling to 0° C.
2. extractionextracted with chloroform
3. dry with materialThe extract was dried over magnesium sulfate
4. customThe residue obtained
5. customafter the removal of the solvent
6. customwas recrystallized in ethyl acetate