Sodium cyanoborohydride → 162100-51-8

HRID 356022Notes

Reaction equation

HRID 356022 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.C([BH3-])#N.[Na+]>C(O)(=O)C>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][NH:6]2

Participants

4

Reactant 2

HCID 5003444Sodium cyanoborohydrideHCID 14419622HCID 14419622, compound

Product 1

HCID 18940894162100-51-8Yield 90%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

4,5-Dichloroindole (D31) was reduced in the usual way with sodium cyanoborohydride in glacial acetic acid to give the title compound (D32) (1.22 g, 90%)

Sources & evidence

ORD record
ord-06b826ef8cd84dc1af17101ff26991fc
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Reaction notes

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