Sodium cyanoborohydride → HCID 10750101, compound

HRID 356026Notes

Reaction equation

HRID 356026 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[Cl:11])[NH:7][CH:6]=[CH:5]2.C([BH3-])#N.[Na+]>C(O)(=O)C>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[Cl:11])[NH:7][CH2:6][CH2:5]2

Participants

4

Reactant 2

HCID 5003444Sodium cyanoborohydrideHCID 104877765,6-dichloro-1H-indole

Product 1

HCID 10750101HCID 10750101, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

5,6-Dichloroindole (D38) was reduced in the usual way with sodium cyanoborohydride in glacial acetic acid to give the title compound (D39) (1.18 g, 90%).

Sources & evidence

ORD record
ord-fa896edfe4b34c0fa74014413e3506a2
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Reaction notes

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