Sodium cyanoborohydride → HCID 18940897, compound

HRID 356031Notes

Reaction equation

[Cl:1][C:2]1[C:10]([S:11][CH3:12])=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.C([BH3-])#N.[Na+]>>[Cl:1][C:2]1[C:10]([S:11][CH3:12])=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][NH:6]2

Participants

Reactant 2

HCID 5003444Sodium cyanoborohydride

HCID 10607997HCID 10607997, compound

Product 1

HCID 18940897HCID 18940897, compoundYield 100.4%

Procedure

4-Chloro-5-methylthioindole (D47) (0.89 g, 4.49mmol) was treated with sodium cyanoborohydride according to the procedure of Description 10 to afford the title compound (0.90 g, 100%) as a pale yellow oil.

Sources & evidence

ORD record: ord-19152ce4ed364dbca3c74cc90f0e889c
Source dataset: uspto-grants-1998_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05834494

Reaction notes

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