Sodium cyanoborohydride → HCID 18940898, compound

HRID 356033Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][C:3]=1[CH2:11][CH3:12].C([BH3-])#N.[Na+]>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][NH:8]2)=[CH:4][C:3]=1[CH2:11][CH3:12]

Participants

Reactant 2

HCID 5003444Sodium cyanoborohydride

HCID 10749855HCID 10749855, compound

Product 1

HCID 18940898HCID 18940898, compoundYield 77.2%

Procedure

6-Chloro-5-ethylindole (D51) (0.62 g, 3.46 mmol) was treated with sodium cyanoborohydride as in the method of Description 10 to give the title compound (0.485 g, 77%) as a yellow oil.

Sources & evidence

ORD record: ord-61fc14fe75b74eeebe4d2165df9e8cb3
Source dataset: uspto-grants-1998_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05834494

Reaction notes

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