Sodium cyanoborohydride → HCID 18940944, compound

HRID 356036Notes

Reaction equation

HRID 356036 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][C:3]=1[CH:11]([CH3:13])[CH3:12].C([BH3-])#N.[Na+]>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][NH:8]2)=[CH:4][C:3]=1[CH:11]([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 5003444Sodium cyanoborohydrideHCID 10774163HCID 10774163, compound

Product 1

HCID 18940944HCID 18940944, compoundYield 79%

Procedure

6-Chloro-5-isopropylindole (D58) (0.5 g, 2.60 mmol) was treated with sodium cyanoborohydride as in the method of Description 10 to give the title compound (0.4 g, 79%) as a yellow oil.

Sources & evidence

ORD record
ord-9798a069180a4146acbb4e08096bde3f
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Reaction notes

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