Hydrogen Bromide → HCID 18940977, compound

HRID 356103Notes

Reaction equation

HRID 356103 reaction equation
[O:1]=[C:2]1[C:11]2[N:10]=[CH:9][CH:8]=[CH:7][C:6]=2[CH2:5][CH2:4][CH2:3]1.[BrH:12].BrBr>C(O)(=O)C>[BrH:12].[Br:12][CH:3]1[C:2](=[O:1])[C:11]2[N:10]=[CH:9][CH:8]=[CH:7][C:6]=2[CH2:5][CH2:4]1

Participants

5

Reactant 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 117447776,7-Dihydro-5H-quinoline-8-one

Product 1

HCID 18940977HCID 18940977, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

To a solution of 0.68 g of 8-oxo-5,6,7,8-tetrahydroquinoline in 25 ml of acetic acid, 2.5 ml of a 25% solution of hydrobromic acid in acetic acid was added, followed by the dropwise addition of 0.235 ml of bromine. After stirring at room temperature for 30 minutes, the solvent was evaporated. The resulting residue was washed with diethyl ether, whereby 1.5 g of 7-bromo-8-oxo-5,6,7,8-tetrahydroquinoline hydrobromide was obtained.

Workup

  1. customthe solvent was evaporated
  2. washThe resulting residue was washed with diethyl ether

Sources & evidence

ORD record
ord-59903bd93f024bb1a6689d4cb4964a81
Source dataset
uspto-grants-1998_11
Patent number
US05834499

Reaction notes

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