Hydrochloric Acid → HCID 18941005, compound

Participants

Reaction Steps

In 6 ml of ethyl acetate, 155 mg of 2-[2-(tert-butoxycarbonylamino)cyclopentyl]-8H-indeno[1,2-d]thiazole was dissolved. Then, 15 ml of a 4N solution of hydrogen chloride in ethyl acetate was added, followed by stirring at room temperature for one hour. The crystals precipitated were collected by filtration, and the crystals were recrystallized from ethyl acetate-methanol, whereby 39 mg of 2-(2-aminocyclopentyl)-8H-indeno[1,2-d]thiazole dihydrochloride was obtained.

Provenance & Evidence