Benzyl Bromide → HCID 18940553, compound

HRID 356143Notes

Reaction equation

HRID 356143 reaction equation
[CH2:1]1[CH:11]2[C:5](=[N:6][C:7]3[CH:16]=[CH:15][CH:14]=[CH:13][C:8]=3[NH:9][C:10]2=[O:12])[CH2:4][CH2:3][CH2:2]1.[CH2:17](Br)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(O)C.CCCCCC>[CH2:17]([N:9]1[C:10](=[O:12])[CH:11]2[CH2:1][CH2:2][CH2:3][CH2:4][C:5]2=[N:6][C:7]2[CH:16]=[CH:15][CH:14]=[CH:13][C:8]1=2)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 14469067HCID 14469067, compound

Product 1

HCID 18940553HCID 18940553, compoundYield 66%

Reagents, catalysts & solvents 1

HCID 21879635Ethanol hexaneSolvent

Procedure

Using 1,2,3,4,10,11a-hexahydro-11H-dibenzo [b,e][1,4]diazepin-11-one and benzyl bromide, the titled compound was synthesized in substantially the same procedure as in Working Example 4. Yield 66%. m.p. 123°-125° C. (ethanol-hexane).

Sources & evidence

ORD record
ord-5931969e6bfd4056970d634791cb7576
Source dataset
uspto-grants-1998_11
Patent number
US05834463

Reaction notes

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