Diethyl Ether → HCID 18940617, compound

HRID 356179Notes

Reaction equation

HRID 356179 reaction equation
[CH2:1]([N:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[C:11]([CH3:19])[CH2:10][C:9]1=[O:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(O[CH2:24][CH3:25])C>>[CH2:1]([N:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[C:11]([CH3:19])[CH:10]([CH2:7]/[CH:6]=[CH:5]/[C:25]2[CH:24]=[CH:4][CH:3]=[CH:2][CH:1]=2)[C:9]1=[O:20])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 3283Diethyl EtherHCID 18940576HCID 18940576, compound

Product 1

HCID 18940617HCID 18940617, compoundYield 69%

Procedure

Using 1-benzyl-4-methyl-1,3-dihydro-1,5-benzodiazepin-2(2H)-one, the title compound was synthesized in substantially the same manner as in Working Example 21 in a yield of 69%, m.p. 152°-154° C. (diethyl ether).

Sources & evidence

ORD record
ord-d07f982e067b417e941227fe35de2ab5
Source dataset
uspto-grants-1998_11
Patent number
US05834463

Reaction notes

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