HCID 18940595, compound → HCID 70109608, compound

HRID 356182Notes

Reaction equation

HRID 356182 reaction equation
[CH2:1]([N:8]1[C:14](=[O:15])[CH:13]2[CH2:16][CH2:17][CH2:18][C:12]2=[N:11][C:10]2[CH:19]=[CH:20][C:21]([Cl:23])=[CH:22][C:9]1=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(OC(=O)C)C.CCCCCC>[CH2:1]([N:8]1[C:14](=[O:15])[C@H:13]2[CH2:16][CH2:17][CH2:18][C@H:12]2[NH:11][C:10]2[CH:19]=[CH:20][C:21]([Cl:23])=[CH:22][C:9]1=2)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 18940595HCID 18940595, compound

Product 1

HCID 70109608HCID 70109608, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using 9-benzyl-7-chloro-2,3,9,10a-tetrahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one, the titled compound was synthesized in substantially the same manner as in Working Example 26 in a yield of 53%, m.p. 160°-163° C. (ethylacetate-hexane).

Sources & evidence

ORD record
ord-1b3eb8c38dc64fbfb14f1ec6e09432fb
Source dataset
uspto-grants-1998_11
Patent number
US05834463

Reaction notes

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