HCID 18940559, compound → HCID 18940542, compound

Participants

Reaction Steps

A suspension of 1-benzyl-4-((E)-styryl)-1,3,4,5-tetrahydro-1,5-benzodiazepin-2(2H)-one (0.51 g, 0.69 mmol) and platinum oxide (50 mg) in methanol (20 ml) was stirred for 3 hours at room temperature under hydrogen atmosphere. The reaction mixture was subjected to filtration. The solvent of the filtration was distilled off, and the residue was crystallized from diethyl ether to give 500 mg (yield 98%) of the titled compound, m.p. 135°-137° C.

Provenance & Evidence