HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Phenylenediamine → HCID 18940605, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Phenylenediamine | HCID 7243 | — |
| Reactant | Methyl 3-oxo-4-phthalimidobutyrate | HCID 2841582 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 18940605 | HCID 18940605 | 81.5% |
Reaction Steps
A mixture of methyl 3-oxo-4-phthalimidobutyrate (15.4 g, 59 mmol), o-phenylenediamine (6.37 g, 59 mmol) and xylene (150 mL) was refluxed for 20 minutes using Dean-Stark apparatus. The reaction mixture was cooled, and resulting crystals were collected by filtration and washed with toluene to give the object compound (15.36 g, 81%), m.p.244°-246° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05834463 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-cc59e5df25e04b23983c00e6c5e1cae6 |
| Source note | uspto-grants-1998_11 |