HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → N-Methyl-N[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]formamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-[3-(3-Methyl-1,2,4-triazolo-[4,3-b]pyridazin-6-yl) phenyl]formamide | HCID 15595683 | — |
| Product | N-Methyl-N[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]formamide | HCID 15595684 | — |
Reaction Steps
A mixture of 2.5 g of N-[3-(3-methyl-1,2,4-triazolo-[4,3-b]-pyridazin-6-yl)phenyl]formamide, 0.56 g of sodium hydride (50% in oil) and 250 ml of dimethylformamide were reacted as described in example 2, giving 1.72 g of the desired product as a white powder, mp 207°-210° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04767765 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-92cf283ca8064e438ede5469e864ac9b |
| Source note | uspto-grants-1988_08 |