3-(4-Hydroxyphenyl)-1-phenylprop-2-en-1-one → NSC179363

HRID 356460Notes

Reaction equation

HRID 356460 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:11])=[CH:4][CH:3]=1>[Pd].C1COCC1>[OH:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][C:10]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)=[O:11])=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 893403-(4-Hydroxyphenyl)-1-phenylprop-2-en-1-one

Product 1

HCID 301514NSC179363

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

The title compound was prepared as described in General Method 3 from 3-(4-hydroxy-phenyl)-1-phenyl-prop-2-en-1-one (25.5 g, 113.6 mmol), 5% Pd on BaSO4 (1.0 g), and THF (400 mL). The catalyst was filtered, and the filtrate was concentrated . The residue was recrystallized from 50% EtOH, to give the title compound, m.p. 118°-119° C.

Workup

  1. customThe title compound was prepared
  2. filtrationThe catalyst was filtered
  3. concentrationthe filtrate was concentrated
  4. customThe residue was recrystallized from 50% EtOH

Sources & evidence

ORD record
ord-5aea69c07c3e45589500fa63fc8694e2
Source dataset
uspto-grants-1998_11
Patent number
US05834506

Reaction notes

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