1-Methyl-4-iodo-1H-pyrazole → 5,11-Dihydro-11-ethyl-5-methyl-2-(1-methylpyrazol-4-yl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

HRID 356596Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 356596
[CH2:1]([N:3]1[C:9]2[N:10]=[CH:11][CH:12]=[CH:13][C:8]=2[C:7](=[O:14])[N:6]([CH3:15])[C:5]2[CH:16]=[CH:17][C:18](OS(C(F)(F)F)(=O)=O)=[N:19][C:4]1=2)[CH3:2].[CH3:28][N:29]1[CH:33]=[C:32](I)[CH:31]=[N:30]1>>[CH2:1]([N:3]1[C:9]2[N:10]=[CH:11][CH:12]=[CH:13][C:8]=2[C:7](=[O:14])[N:6]([CH3:15])[C:5]2[CH:16]=[CH:17][C:18]([C:32]3[CH:31]=[N:30][N:29]([CH3:28])[CH:33]=3)=[N:19][C:4]1=2)[CH3:2]

Komponenten

3

Edukt 2

HCID 27347731-Methyl-4-iodo-1H-pyrazoleHCID 107160835,11-Dihydro-11-ethyl-5-methyl-2-trifluoromethanesulfonyloxy-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Produkt 1

HCID 159562795,11-Dihydro-11-ethyl-5-methyl-2-(1-methylpyrazol-4-yl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Versuchsvorschrift

The title compound (mp 65°-67° C.) was prepared from 5,11-dihydro-11-ethyl-5-methyl-2-trifluoromethanesulfonyloxy-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one and N-methyl-4-iodopyrazole in a manner analogous to that described in Example 1.

Quellen und Nachweise

ORD-Eintrag
ord-df396e1ee6cb452189b002f2934a5880
Quelldatensatz
uspto-grants-1998_11
Patentnummer
US05837704

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