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HRID356604

反应详情

EQUATION

反应方程式

HRID 356604 的结构方程式

REACTANTS

反应物

3
结构：CCC[CH2][Sn]([Cl])([CH2]CCC)[CH2]CCC
HCID15096

Tributyltin chloride

C12H27ClSn

结构：CC(C)(C)OC(=O)n1cccc1
HCID643494

N-Boc-pyrrole

C9H13NO2

结构：CC(C)[N-]C(C)C.CCC[CH2][Sn]([CH2]CCC)([CH2]CCC)[c]1cccn1C(=O)OC(C)(C)C.[Li+]
HCID86753332

未命名化合物

PRODUCTS

生成物

1
结构：CCC[CH2][Sn]([CH2]CCC)([CH2]CCC)[c]1cccn1C(=O)OC(C)(C)C
HCID11363059

1H-Pyrrole-1-carboxylic acid, 2-(tributylstannyl)-, 1,1-dimethylethyl ester

C21H39NO2Sn

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

2 次

PROCEDURE

实验过程

(1-(t-Butoxycarbonyl)pyrrol-2-yl)tributyltin LDA in dry THF (1.2M, 0.83 mL) was slowly added to a cooled (-78° C.) solution of 1-(t-butoxycarbonyl)pyrrole (0.67 g) in dry THF (5 mL). After stirring for 3 h, tributyltin chloride (0.65 g) was slowly added, and the mixture was allowed to warm to room temperature overnight. The solvent was removed to provide (1-(t-butoxycarbonyl)pyrrol-2-yl)tributyltin, suitable for use in the next reaction.

WORKUP

后处理

  1. customThe solvent was removed