HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,6-Dichloro-2-(3-methoxy-benzyl)-5-phenoxy-pyrimidine → 5-Isopropyl-pyridine-2-sulphonic acid [6-chloro-2-(3-methoxy-benzyl)-5-phenoxy-pyrimidin-4-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,6-Dichloro-2-(3-methoxy-benzyl)-5-phenoxy-pyrimidine | HCID 18938913 | — |
| Reactant | 5-Isopropyl-pyridine-2-sulphonamide potassium | HCID 69289451 | — |
| Product | 5-Isopropyl-pyridine-2-sulphonic acid [6-chloro-2-(3-methoxy-benzyl)-5-phenoxy-pyrimidin-4-yl]-amide | HCID 86753336 | — |
Reaction Steps
In analogy to Example 45, by reacting 4,6-dichloro-2-(3-methoxy-benzyl)-5-phenoxy-pyrimidine with potassium 5-isopropyl-pyridine-2-sulphonamide there was obtained 5-isopropyl-pyridine-2-sulphonic acid [6-chloro-2-(3-methoxy-benzyl)-5-phenoxy-pyrimidin-4-yl]-amide as a yellow foam. MS: 523 (M-H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05837708 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-eb8b037486ed4fb5919ec3a88adef99a |
| Source note | uspto-grants-1998_11 |