HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(2-Hydroxyethylthio)thioxanthone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Mercaptoethanol | HCID 1567 | — |
| Reactant | Dimethylacetamide | HCID 31374 | — |
| Reactant | 2-Chlorothioxanthone | HCID 618848 | — |
| Reactant | Potassium | HCID 5462222 | — |
| Product | 2-(2-Hydroxyethylthio)thioxanthone | HCID 18939138 | — |
Reaction Steps
5.6 g (0.0225 mol) of 2-chlorothioxanthone and 2.6 g (0.0225 mol) of the potassium salt of 2-mercaptoethanol are stirred for 18 hours in 20 mol of N,N-dimethylacetamide at 100° C. The reaction mixture is then poured into 2N hydro-chloric acid and extracted with ethyl acetate. After conventional work-up and chromatographic purification, 3.5 g of the analytically pure compound IIIa of melting point 94° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05837746 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-d2dbb9a41f3b4454a5508942d0219ba3 |
| Source note | uspto-grants-1998_11 |