反应详情

To a suspension of 12-aminododecanoic acid (5.00 g, 23.3 mmol) in anhydrous MeOH (90 mL) was introduced hydrogen chloride gas for 25 minutes, during which time the suspension became clear. The solution was then stirred at room temperature for 3 hours and the solvent was removed in vacuo. The white solid residue was dissolved in H2O. Solid NaHCO3 was added to neutralize the solution to pH 8-9. The white precipitates thus formed were collected by vacuum filtration (5.20 g) (Yield: 98%).

1. customthe solvent was removed in vacuo
2. dissolutionThe white solid residue was dissolved in H2O
3. additionSolid NaHCO3 was added
4. customThe white precipitates thus
5. customformed
6. filtrationwere collected by vacuum filtration (5.20 g) (Yield: 98%)