Phosphoric Acid → HCID 67615143, compound

HRID 356997Notes

Reaction equation

[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=[CH:12][C:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[N:16]=[CH:15][CH:14]=1.[P:23](=O)([OH:26])([OH:25])[OH:24].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>>[P:23]([O:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=[CH:12][C:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[N:16]=[CH:15][CH:14]=1)([OH:26])([OH:25])=[O:24]

Participants

Reactant 3

HCID 1004Phosphoric Acid

HCID 14812Phosphorus oxide (P4O10)

HCID 54130696HCID 54130696, compound

Product 1

HCID 67615143HCID 67615143, compoundYield 50%

Conditions

Temperature: 60 °C

Procedure

A mixture of 5-hydroxy-3-(quinol-4-ylmethylene)-2-oxindole (2.883 g, 10 mmol) and phosphoric acid 85% (13 g) and phosphorous pentoxide (10 g) was heated for 2 h at 60° C. The usual work-up gave the title compound in about 50% yield.

Sources & evidence

ORD record: ord-025fad3f915d4228874720089fd13d9a
Source dataset: uspto-grants-1998_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05840745

Reaction notes

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