1-Bromo-2-Chloroethane → HCID 18936671, compound

HRID 357005Notes

Reaction equation

HRID 357005 reaction equation
[SH:1][C:2]1[N:7]2[CH:8]=[CH:9][N:10]=[C:6]2[CH:5]=[CH:4][CH:3]=1.C(N(CC)CC)C.Br[CH2:19][CH2:20][Cl:21]>>[Cl:21][CH2:20][CH2:19][S:1][C:2]1[N:7]2[CH:8]=[CH:9][N:10]=[C:6]2[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 78491-Bromo-2-ChloroethaneHCID 8471TriethylamineHCID 178418687HCID 178418687, compound

Product 1

HCID 18936671HCID 18936671, compound

Procedure

Using 3.0 g (20 mmol) of 5-mercaptoimidazo[1,2-a]pyridine, 2.79 ml (20 mmol) of triethylamine and 1.66 ml (20 mmol) of 1-bromo-2-chloroethane, the same procedure as in Reference Example 1 was followed, to yield 2.29 g (54.0%, light brown oily substance) of the desired product.

Sources & evidence

ORD record
ord-8f8c17b413ef4e6f95a3c32c2659828e
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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