Triethylamine → HCID 18936796, compound

HRID 357012Notes

Reaction equation

HRID 357012 reaction equation
Cl.[OH:2][CH2:3][CH2:4][CH2:5][C:6]1[N:11]2[CH:12]=[CH:13][N:14]=[C:10]2[CH:9]=[CH:8][CH:7]=1.C(N(CC)CC)C.[CH3:22][S:23](Cl)(=[O:25])=[O:24]>>[CH3:22][S:23]([O:2][CH2:3][CH2:4][CH2:5][C:6]1[N:11]2[CH:12]=[CH:13][N:14]=[C:10]2[CH:9]=[CH:8][CH:7]=1)(=[O:25])=[O:24]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 18936846HCID 18936846, compound

Product 1

HCID 18936796HCID 18936796, compound

Procedure

Using 2.55 g (12 mmol) of 5-(3-hydroxypropyl)imidazo-[1,2-a]pyridine hydrochloride, 3.90 ml (28 mmol) of triethylamine and 1.08 ml (14 mmol) of methanesulfonyl chloride, the same procedure as in Reference Example 8 was followed, to yield 5-(3-methanesulfonyloxypropyl)imidazo-[1,2-a]pyridine.

Sources & evidence

ORD record
ord-c3a8a14f88604da0bf530f511eefa65e
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

Loading…