HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetaldehyde → 3-[4-(Imidazo[1,2-a]pyridin-8-yloxy)butyl]oxazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetaldehyde | HCID 33 | — |
| Reactant | 3-[4-(2-Aminopyridin-3-yloxy)butyl]oxazolidine-2,4-dione | HCID 18936721 | — |
| Product | 3-[4-(Imidazo[1,2-a]pyridin-8-yloxy)butyl]oxazolidine-2,4-dione | HCID 18936739 | — |
Reaction Steps
Using 6.63 g (25 mnmol) of 3-[4-(2-aminopyridin-3-yloxy)butyl]oxazolidine-2,4-dione and 25 ml of a 40% chloroacetaldehyde solution, the same procedure as in Reference Example 18 was followed, to yield 6.48 g (89.5%, yellow oily substance) of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05840732 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-5dcf9e7728964d3c82a9fe8ead9d4460 |
| Source note | uspto-grants-1998_11 |