Hydrochloric Acid → HCID 73472891, compound

HRID 357036Notes

Reaction equation

HRID 357036 reaction equation
[CH:1](=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][CH2:13][S:14][C:15]2[N:20]3[CH:21]=[CH:22][N:23]=[C:19]3[CH:18]=[CH:17][CH:16]=2)[C:6]1=[O:24])[CH2:2][CH2:3][CH3:4].[ClH:25]>CO>[ClH:25].[CH:1](=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][CH2:13][S:14][C:15]2[N:20]3[CH:21]=[CH:22][N:23]=[C:19]3[CH:18]=[CH:17][CH:16]=2)[C:6]1=[O:24])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57126325HCID 57126325, compound

Product 1

HCID 73472891HCID 73472891, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1.27 g (3.51 mmol) of 5-butylidene-3-[3-(imidazo[1,2-a]pyridin-5-ylthio)propyl]thiazolidine-2,4-dione in 30 ml of methanol, 0.35 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.33 g (95.4%, light orange solid) of the desired product.

Workup

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

Sources & evidence

ORD record
ord-d63a971c768e4d48a9130c85491f8628
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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