Hydrochloric Acid → HCID 73472947, compound

HRID 357038Notes

Reaction equation

HRID 357038 reaction equation
[CH:1](=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][S:13][C:14]2[N:19]3[CH:20]=[CH:21][N:22]=[C:18]3[CH:17]=[CH:16][CH:15]=2)[C:6]1=[O:23])[CH2:2][CH2:3][CH3:4].[ClH:24]>CO>[ClH:24].[CH:1](=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][S:13][C:14]2[N:19]3[CH:20]=[CH:21][N:22]=[C:18]3[CH:17]=[CH:16][CH:15]=2)[C:6]1=[O:23])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57121133HCID 57121133, compound

Product 1

HCID 73472947HCID 73472947, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 0.723 g (2.1 mmol) of 5-butylidene-3-[2-(imidazo[1,2-a]pyridin-5-ylthio)ethyl]thiazolidine-2,4-dione in 20 ml of methanol, 0.25 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 0.755 g (94.2%, light yellow solid) of the desired product.

Workup

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

Sources & evidence

ORD record
ord-e89094c775744bf88d2371e4627c383f
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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