Hydrochloric Acid → HCID 73472944, compound

HRID 357042Notes

Reaction equation

HRID 357042 reaction equation
[CH:1](=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][CH2:13][CH2:14][C:15]2[N:20]3[CH:21]=[CH:22][N:23]=[C:19]3[CH:18]=[CH:17][CH:16]=2)[C:6]1=[O:24])[CH2:2][CH2:3][CH3:4].[ClH:25]>CO>[ClH:25].[CH:1](=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][CH2:13][CH2:14][C:15]2[N:20]3[CH:21]=[CH:22][N:23]=[C:19]3[CH:18]=[CH:17][CH:16]=2)[C:6]1=[O:24])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57132710HCID 57132710, compound

Product 1

HCID 73472944HCID 73472944, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1.08 g (3.14 mmol) of 5-butylidene-3-[4-(imidazo[1,2-a]pyridin-5-yl)butyl]thiazolidine-2,4-dione in 50 ml of methanol, 0.4 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.10 g (92.3%, yellow oily substance) of the desired product.

Workup

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

Sources & evidence

ORD record
ord-1e27c82a87b64511ad74c292c99062cd
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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