HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Butylidene-3-[2-(imidazo[1,2-a]pyridin-5-yl)ethyl]thiazolidine-2,4-dione hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-Butylidene-3-[2-(imidazo[1,2-a]pyridin-5-yl)ethyl]thiazolidine-2,4-dione | HCID 57292319 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Butylidene-3-[2-(imidazo[1,2-a]pyridin-5-yl)ethyl]thiazolidine-2,4-dione hydrochloride | HCID 73472907 | — |
Reaction Steps
To a solution of 1.15 g (3.65 mmol) of 5-butylidene-3-[2-(imidazo[1,2-a]pyridin-5-yl)ethyl]thiazolidine-2,4-dione in 50 ml of methanol, 0.33 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.00 g (77.9%, light yellow solid) of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05840732 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-393521cebc0b49828745cff280617e15 |
| Source note | uspto-grants-1998_11 |