反应详情

To a solution of 330 mg (0.76 mmol) of 5-(1-methylpiperazin-4-yl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 10 ml of methanol, concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 360 mg (82.0%, white crystal) of the desired product.

1. distillationAfter the solvent was distilled off
2. washthe residue was washed with diethyl ether