HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylsulfinyl)butyl]thiazolidine-2,4-dione hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylsulfinyl)butyl]thiazolidine-2,4-dione | HCID 57305719 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylsulfinyl)butyl]thiazolidine-2,4-dione hydrochloride | HCID 73472914 | — |
Reaction Steps
To a solution of 287 mg (0.73 mmol) of 5-butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylsulfinyl)butyl]thiazolidine-2,4-dione in 10 ml of methanol, 0.10 ml of concentrated hydrochloric acid was added, followed by stirring, after which the solvent was distilled off. The residue was washed with diethyl ether to yield 280 mg (89.6%, light yellow foamy substance) of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05840732 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-8960f2c2765742829c8f96599e461e13 |
| Source note | uspto-grants-1998_11 |