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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 357139Generated: October 31, 2026

Hydrochloric Acid → 5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylsulfinyl)butyl]thiazolidine-2,4-dione hydrochloride

https://huagongshe.com/reaction/357139

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylsulfinyl)butyl]thiazolidine-2,4-dioneHCID 57305719—
SolventMethanolHCID 887—
Product5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylsulfinyl)butyl]thiazolidine-2,4-dione hydrochlorideHCID 73472914—

Reaction Steps

To a solution of 287 mg (0.73 mmol) of 5-butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylsulfinyl)butyl]thiazolidine-2,4-dione in 10 ml of methanol, 0.10 ml of concentrated hydrochloric acid was added, followed by stirring, after which the solvent was distilled off. The residue was washed with diethyl ether to yield 280 mg (89.6%, light yellow foamy substance) of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05840732
Source datasetuspto-grants-1998_11
ORD IDord-8960f2c2765742829c8f96599e461e13
Source noteuspto-grants-1998_11