Hydrochloric Acid → HCID 73472927, compound

HRID 357167Notes

Reaction equation

HRID 357167 reaction equation
[CH:1](=[C:8]1[S:12][C:11](=[O:13])[N:10]([CH2:14][CH2:15][CH2:16][CH2:17][S:18][C:19]2[N:24]3[CH:25]=[CH:26][N:27]=[C:23]3[CH:22]=[CH:21][CH:20]=2)[C:9]1=[O:28])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[ClH:29]>CO>[ClH:29].[CH:1](=[C:8]1[S:12][C:11](=[O:13])[N:10]([CH2:14][CH2:15][CH2:16][CH2:17][S:18][C:19]2[N:24]3[CH:25]=[CH:26][N:27]=[C:23]3[CH:22]=[CH:21][CH:20]=2)[C:9]1=[O:28])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57323551HCID 57323551, compound

Product 1

HCID 73472927HCID 73472927, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1.99 g (4.76 mmol) of 5-heptylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 30 ml of methanol, 0.42 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 2.31 g (quant., yellow-orange oily substance) of the desired product.

Workup

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

Sources & evidence

ORD record
ord-8c126b5389e841778c5d5256621c6def
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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