Hydrochloric Acid → HCID 73472910, compound

HRID 357171Notes

Reaction equation

HRID 357171 reaction equation
[CH:1](=[C:7]1[S:11][C:10](=[O:12])[N:9]([CH2:13][CH2:14][CH2:15][CH2:16][S:17][C:18]2[N:23]3[CH:24]=[CH:25][N:26]=[C:22]3[CH:21]=[CH:20][CH:19]=2)[C:8]1=[O:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[ClH:28]>CO>[ClH:28].[CH:1](=[C:7]1[S:11][C:10](=[O:12])[N:9]([CH2:13][CH2:14][CH2:15][CH2:16][S:17][C:18]2[N:23]3[CH:24]=[CH:25][N:26]=[C:22]3[CH:21]=[CH:20][CH:19]=2)[C:8]1=[O:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57070718HCID 57070718, compound

Product 1

HCID 73472910HCID 73472910, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1.77 g (4.39 mmol) of 5-hexylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 30 ml of methanol, 0.42 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.89 g (97.9%, yellow-orange oily substance) of the desired product.

Workup

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

Sources & evidence

ORD record
ord-6f4e49332d8c4e359733727196bc15e5
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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