Hydrochloric Acid → HCID 73472975, compound

HRID 357173Notes

Reaction equation

HRID 357173 reaction equation
[CH:1](=[C:9]1[S:13][C:12](=[O:14])[N:11]([CH2:15][CH2:16][CH2:17][CH2:18][S:19][C:20]2[N:25]3[CH:26]=[CH:27][N:28]=[C:24]3[CH:23]=[CH:22][CH:21]=2)[C:10]1=[O:29])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[ClH:30]>CO>[ClH:30].[CH:1](=[C:9]1[S:13][C:12](=[O:14])[N:11]([CH2:15][CH2:16][CH2:17][CH2:18][S:19][C:20]2[N:25]3[CH:26]=[CH:27][N:28]=[C:24]3[CH:23]=[CH:22][CH:21]=2)[C:10]1=[O:29])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57255689HCID 57255689, compound

Product 1

HCID 73472975HCID 73472975, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1.54 g (3.57 mmol) of 5-octylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 30 ml of methanol, 0.34 ml of concentrated hydro-chloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.65 g (98.7%, yellow-orange oily substance) of the desires product.

Workup

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether
  3. customto yield 1.65 g (98.7%, yellow-orange oily substance) of the desires product

Sources & evidence

ORD record
ord-59f7d190d3b442c0aa47fabba697b8d7
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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