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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 357180Generated: October 27, 2026

Hydrochloric Acid → 5-Ethylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione hydrochloride

https://huagongshe.com/reaction/357180

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Ethylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dioneHCID 57080530—
SolventMethanolHCID 887—
Product5-Ethylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione hydrochlorideHCID 70202597—

Reaction Steps

To a solution of 77 mg (0.23 mmol) of 5-ethylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione in 5 ml of methanol, 0.10 ml of concentrated hydro-chloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 90 mg (quant., brown oily substance) of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05840732
Source datasetuspto-grants-1998_11
ORD IDord-2165adceff1344e6a14c29b07df924a7
Source noteuspto-grants-1998_11